Tag Archive | "aspirin"

Aspirin May Do More For Men Than Relieve Minor Aches and Pains


Aspirin has long been known to reduce inflammation and relieve minor aches and pains. But promising evidence has surfaced suggesting that aspirin can help drastically cut deaths among prostate cancer patients.

Dr. Kevin Choe of the University of Texas Southwestern Medical School in Dallas says men with prostate cancer who take anti-coagulants such as aspirin in addition to radiation therapy or surgery may be able to cut their risk of dying of cancer by more than half.

“Findings from this study—involving 5,275 men with localized prostate cancer—are promising, but, further studies are necessary before the addition of aspirin to prostate cancer therapy becomes standard treatment,” Choe, the study author, said.

Other studies have been conducted to test similar predictions, but many have had mixed results with anti-coagulants.

“If the cancer has already metastasized, then anti-coagulants may not be as beneficial,” explains Choe.
This study also found that aspirin led to the greatest benefits, when compared to other anti-coagulants.

In addition, aspirin had the most benefit for those patients with the most aggressive form of cancer.

“This is exciting news as patients with high-risk disease have the most aggressive cancer, with a high likelihood of dying from the disease, and the treatment options are currently limited,” Choe notes.

Posted in Prostate Health, Prostate InflammationComments (2)

Aspirin and Statins May Obscure Prostate Cancer


Most men learn they have prostate cancer after a blood test reveals elevated prostate-specific antigen (PSA) levels, prompting a biopsy. Medicines that artificially lower PSA levels could, in theory, hide elevations that provide early warnings of possible cancer.

A recent study correlated the use of cholesterol-lowering drugs called statins to lower PSA levels. Researchers examined PSA levels of 1,214 military veterans before and after they started taking a statin. The statins caused a median decline in PSA of 4.1%, and changes in PSA were strongly associated with the statin dose and changes in LDL cholesterol.

Additionally, an unpublished study presented at a meeting of the American Association for reported that men in the Nashville Men’s Health Study who took aspirin regularly had PSA levels that were 9% lower on average than those in men who didn’t take aspirin.

Although the changes in PSA reported in the studies weren’t large, researchers expressed concern that the drugs could disguise fluctuations in PSA and interfere with prostate cancer detection. Although it is also possible that statins and aspirin actually help fight prostate cancer, more and longer-term studies are needed to determine if that is the reason for the PSA decrease.

The study’s authors recommend that you tell your urologist if you are taking aspirin, statins or both so that he or she can better evaluate your risk for prostate cancer.

Posted in Prostate HealthComments (1)


 

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